Oral Allergy Syndrome (OAS)

Definition:

  • Patient is allergic to birch, grass or ragweed pollens which contain a protein found in many plants therefore cross reacting with a variety of fruits and nuts
  • Not actually allergic to the fruits or nuts themselves
Cross- reactivity:

Pollen                                  Cross-Reacting Foods
____________________________________________________________________________________

Birch                                      Almonds       Kiwi
                                                Apple            Parsley
                                                Apricots        Parsnip
                                                Carrots          Peach
                                                Celery            Pear
                                                Cherry           Plum
                                                Fennel           Potato
                                                Hazelnut        Walnut
_____________________________________________________________________________________

Ragweed                               Banana            Honeydew
                                                Cantaloupe      Watermelon
                                                Cucumber        Zucchini
_____________________________________________________________________________________

Grass                                     Celery
                                                Buckwheat
                                                Potato
                                                Melon
_____________________________________________________________________________________

Symptoms (to fresh fruits and nuts)
  • Tingling/itchy mouth, lips, throat
  • Possible throat tightening, lip swelling, itchy ears
  • Can eat the foods cooked or processed
  • Does not usually progress to anaphylaxis
Diagnosis
  • By clinical history mainly
  • Skin testing to commercial extracts usually negative, but skin test positive on fresh food testing
  • Skin test positive to cross-reacting pollen (birch, grass, ragweed)
Treatment
  • Avoid fresh fruit or nuts.  May eat the fruits cooked or processed
  • Usually does not require Epipen unless has symptoms of throat closing or other systemic symptoms or has positive skin test to the commercial extracts
*** Created by Dr. Ellie Tsai MD, FRCPC Kingston Allergy and Asthma 613-546-6673***

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